Medicinal-oil preparation.



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'To all whom t may concern.'

Be it known that Lllnnnr V. DUNHAM, a citizen of the United States'ot America residing at Brattleboro, in the county ed Windham and State of Vermont, have invented certain neul and useful lmproveniente in Medicinal-@il Pre arations, oi which the ollovving'is a speci "'oation.

The present inventionrelates to the pro` duction of mixtures containing medicinal oils, in asolid stable condition, invvhich the .taste et the oil 'is largely masked by the oil is in an attenuated dnely dividedA condi. tion, 4the product containing the oil in such a containing the oil in other ingredientspresent, and in which the condition that upon mixing,l the product with water at' ordinary temperatures. thev entire' yteinture completely ernulsies, produoing a' thorough mixture or emulsion which' is stable under ordi-nary conditions for a rea` sonable length ottime, whereby the oil is l nous material and the oil, which, mixture can be allowed to stand Mlor along time Without separation o' material amounts olf oil. Pllllnis y to ter which the mixture ,is thendried anden suitable oonditions to preserve lits ready solubility, aildried material maybe pul- Verized. L; i ln the dry condition the product 'will keep `tor llong periods'of ma; Without deterioration, and the product .can subsequently be" mined with Water, forl example, at ordinary temperature to'produce a rather permanent emulsion Without the separation 4ont' any otlieoil.'

exemples olllbilygniaterial tolbe n i ployed, lll mention'castor oil and cod liverV oi' l,;'which 'are exampleso fatty oils, which are extensively. used kin medicines, but which oils'arexnot always readily assimilated by the digestiveorgans-of humans, particularly invalide, Whose' digestive system 'is .relapeoitlcatlon of Letters Patent.

Patented Apr., 29, 1919.

Application led eeptember 4l, lille. Ateriel lilo. 25955592.

tively Weak, and Aalso l mention paraillnum lif'juiduin, which oil can be treated in accordance with the present process. As 'the preferred albuminous material to employ, casein treated as described below is by tar the most suitable, as when using this ma.-

terial l can employ an amount or oil which will constitute up to two-thirds, or even slightly' more, of the total Weight of the finished product. Another 'fairly suitable -albuminous material is egg, which may be employed either as raw e0 egg White, egg yolk ordried egg redsso ved. ln some 1nstances, as 'Where only a relatively small amount ot Aoil is to be incorporated, concentrated, Vmilk or' milk powder mixed 'with Water may be employed..

` As a specific example of the process, to

which the invention is not limited, ll give the following: 100 parts of casein are dissolved in Water, (containing a little alkali, e. g., NaHC,) and to this solution is added 100 parts ot cod liver oil. violently agitated in order to emulsily the oil in the casein solution, and the mixture is then passed through a homogenizer under pressure in the vvell lmovvn Way in order to produce a 'completely homogeneous liquid mass. This mass is then dried in any suitable manner, tor example, in a vacuum drier, andthe resultingn mixture is pulverizeda vThe resulting product-'may contain about of casein and 50% et cod liver oil. The mixture, when stirred up with cold Water, 'forros a relatively stable elnulsion, `which can stand lor several. hoursl vvithout separation el* oil.

At the time of producing 'the original ulsion et the cod liver oil and casein so- The mixture is then lution a small amount of a davorino; nia

terial, suchas oil o'l cinnamon, can be added. llt is also to be understood that other medicinal agents can be added to' the solution il desired, for eaainplmsalts, active principles of plants, enzyme, and the like or flavoring agents, or agents capableof covering` up the Aodor or taste of the oil.

W ith cod liver oil particularly suitable medicinal materials are phosphate and hypophosphites.

lt 1ste be understood that the maximum temperature employed in the drying operation depends upon the particular materials under treatment, particularly-the End of albuminous material employed. This is especially important'in" connection with the use of eggs or eggvvhitefas the emulsifying I liquid.

T he temperature must not be so high as to injure the albumiuous material or to decrease its solubility.

'llhe proportions employed can be widely varied, thus I may use from a proportion of three parts of casein to one of oil, up to one part of casein to two or even more parts of Olla ln producing the original solution of albuminous material in which to emulsii'y the oil, the best practice is to add a suliicient amount of albuminous material to produce a relatively concentrated and relatively viscous solution. For this purpose a neutral or very slightly alkaline solution of casein of about 20% strength is suitable.

The production of edible materials generally, by the employment of edible fatty oils instead of medicinal oils, is not broadly claimed herein but in my copending appllcation No. 261,800 Iiled November 9, 1918.

ll claim:

1. As an article of manufacture, a light, dry, relatively finely divided intimate mixturc comprising an albuminous material and an ingestible medicinal oil, said oil being disseminated in a finely divided state throughout the mixture to be largely masked therein, said albuminous material being 2. A process which comprises emulsitying an ingestible medicinal oil in a solution' of a Water-soluble albuminous material such solution having a greater concentration as to albuminous material than has ordinary milk, the amount of oil being not less than about oneehalf ot the amount of such albuminous material in the solution, homogenizing the emulsion and drying the product.

3. A process which comprises emulsintyinggP an ingestible medicinal oil ina viscous casein solution, homogenizing` the emulsion and drying the product.

d Ll. As a new article of manufacture a light dicinal oil, said oil being disseminated in a finely divided state throughout the rnintun to be largely masked therein, said casein being present in suiiicient quantity to produce upon mixing the product with water an intimate practically stable emulsion, largely free from strong taste or odor.

lln testimony whereof ll ama my signature.

, HENRY V. DUNHAM.

relatively finely divided intimate nnn- .ture comprising casein and an ingestible nie- 

